Description
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Doctors primarily prescribe zolpidem (sold under brand names like Ambien) for short-term treatment of insomnia. Medical guidelines advise using it only after patients try counseling and behavioral modifications.
The medication:
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Reduces time to fall asleep by ~15 minutes
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Helps maintain sleep longer at higher doses
Available in oral tablets, sublingual tablets, and spray formulations, zolpidem acts as a sedative-hypnotic that balances brain chemicals disrupted in insomnia patients.
Uses
Zolpidem for Insomnia Treatment
Zolpidem (brand names: Ambien, Intermezzo, Edluar, Zolpimist) treats insomnia through different formulations:
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Immediate-Release Forms
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Ambien/Edluar/Zolpimist: Help you fall asleep at bedtime
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Intermezzo: Helps you fall back asleep if you wake up midnight
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Extended-Release (Ambien CR)
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Fast-dissolving layer: Helps you fall asleep quickly
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Slow-release layer: Helps you stay asleep longer
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Side Effects
Common side effects include daytime sleepiness, headache, nausea, and diarrhea. Other side effects include memory problems, hallucinations, and abuse.
In 2013, the FDA reduced zolpidem’s recommended dose due to concerns about next-morning impairment. Patients should avoid driving the next morning, especially after taking higher doses or the extended-release formulation.
While flumazenil can reverse zolpidem’s effects, healthcare providers typically recommend only supportive care for overdoses.
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