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Zolpidem, sold under the brand name Ambien, among others, is a medication primarily used for the short term treatment of sleeping problems. Guidelines recommend that it be used only after counselling and behavioral changes have been tried. It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer. It is taken by mouth and is available in conventional tablets or sublingual tablets and oral spray. Zolpidem is a sedative, also called a hypnotic. It affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).
Zolpidem is used to treat insomnia. The immediate-release forms are Ambien, Intermezzo, Edluar, and Zolpimist, which are used to help you fall asleep. The extended-release form of zolpidem is Ambien CR which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep. Ambien is used to help you fall asleep when you first go to bed. Intermezzo is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping. Ambien is used to help you fall asleep when you first go to bed. Intermezzo is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping.
Common side effects include daytime sleepiness, headache, nausea, and diarrhea. Other side effects include memory problems, hallucinations, and abuse. The recommended dose was decreased in 2013 due to next-morning impairment. Additionally, driving the next morning is not recommended with either higher doses or the long-acting formulation. While flumazenil can reverse zolpidem’s effects, usually supportive care is all that is recommended in overdose.
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