Description

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Methaqualone, under the brand name Quaaludes in the US and Mandrax in the UK, is a sedative and hypnotic drug. It belongs to the group of medicines called quinazolinone You can Buy Quaaludes Online safely here.

The sedative–hypnotic activity of methaqualone was initially noted by researchers in the 1950s. In 1962, methaqualone was licensed in the US by Wallace and Tiernan. Its use rose to a greater level in the early 1970s as a hypnotic, for the treatment of insomnia(sleeping disorder), and as a narcotic and muscle relaxant.

Uses

Methaqualone is a depressant that increases the activity of the GABA receptors in the brain and nervous system. When GABA activity increases, blood pressure drops and the breathing and pulse rates slow, leading to a state of deep relaxation. These properties explain why methaqualone was originally mainly prescribed for insomnia. Methaqualone works well in the bloodstream within several hours, with a
half-life of 20–60 hours. Regular users build up a physical tolerance, requiring larger doses for the same effect. Overdose can lead to nervous system shutdown, coma and death.

Pregnant women or breastfeeding mothers should not use methaqualone.

Pharmaceutical companies Rorer and Lemmon manufactured methaqualone in the United States under the brand name Quaalude. The tablets bore the stamped number 714, leading users to commonly call them:

• “714s”

• “Lemmons”

• “Lemmon 714”

. Methaqualone was also manufactured in the US under the trade names Sopor and Parest. After the legal manufacture of the drug ended in the United States in
1982, underground laboratories in Mexico continued the illegal manufacture of methaqualone all through the 1980s, continuing the use of the “714” stamp until their popularity waned in the early 1990s.

Methaqualone is one of the most commonly used recreational drugs in South Africa and small pharmacies smuggle this
medication into the United States, Canada and Britain.

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By 1965, it was the most commonly prescribed sedative in Britain, where it has been sold legally under the names Malsed, Malsedin, and Renoval.

In 1965, Roussel Laboratories (now Sanofi-Aventis) introduced Mandrax, a sedative combining methaqualone with an antihistamine. The medication gained significant popularity, becoming the sixth-best-selling sedative in the U.S. by 1972 under the brand name Quaalude.

American pharmaceutical firm William H. Rorer (based in Fort Washington, Pennsylvania) originally manufactured Quaaludes in 1965 before other companies began production.

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Methaqualone is a common recreational and self-medication drug in South Africa and other of the former Frontline States, including Mozambique, Angola, Zambia and Zimbabwe.

The apartheid-era South African government’s Project Coast, led by Dr. Wouter Basson, continues to produce this medication in both powder and tablet forms.

During development, researchers considered multiple substances for non-lethal riot control, including:

• Methaqualone and MDMA

• Cocaine and other empathogens

• Aphrodisiac compounds

• Muscle relaxants

• Anticholinergic deliriants (for incapacitation)

Methaqualone is likewise a minor product of drug labs in Lebanon’s Biqa Valley (which is a supplier to African markets) and in all quaaludes for sale

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